2Y5L: orally active aminopyridines as inhibitors of tetrameric fructose 1,6- bisphosphatase

PDB ID: 2Y5LDownload
MMDB ID: 90561
PDB Deposition Date: 2011/1/14
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 2Y5L: tetrameric; determined by author and by software (PISA)
Molecular Components in 2Y5L
Label Count Molecule
Proteins (4 molecules)
4
Fructose-1,6-bisphosphatase 1
(Gene symbol: FBP1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
N-{[(2Z)-5-bromo-1,3-thiazol-2(3H)-ylidene]carbamoyl}-3-chlorobenzenesulfonamideN-{[(2Z)-5-bromo-1,3-thiazol-2(3H)-ylidene]carbamoyl}-3-chlorobenzenesulfonamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303